Democrats predict passing Trump's 'big, beautiful bill' will cost many Republicans their seats

And Majority Whip Rep. Tom Emmer of Minnesota said that House Republicans have "shown time and time again that we deliver for the American people, especially when it matters most."

And Democratic Congressional Campaign Committee chair Rep. Suzan DelBene of Washington State said in a Fox News Digital interview ahead of the final House vote that "we're going to hold Republicans accountable, and there will be a price to pay."

"House Democrats just signed their own political death warrant. Voters won't forget how they betrayed working families. And Republicans won't let them," NRCC spokesman Mike Marinella argued in a statement.

The GOP-crafted measure is stuffed full of Trump's campaign trail promises and second-term priorities on tax cuts, immigration, defense, energy and the debt limit. It includes extending his signature 2017 tax cuts and eliminating taxes on tips and overtime pay, providing billions for border security and codifying his controversial immigration crackdown.

As Democrats attack the measure, they're highlighting the GOP's proposed restructuring of Medicaid-the nearly 60-year-old federal program that provides health coverage to roughly 71 million low-income Americans.

"Let's be clear, all Republicans are talking about right now is how many people and how fast they're going to take away healthcare. They have these huge cuts to Medicaid, 14 million people lose healthcare across the country, and they're talking about how fast they can do that," said DelBene.

Schumer argued that "there's nothing beautiful about stripping away people's healthcare, forcing kids to go hungry, denying communities the resources they need, and increasing poverty."

And Martin claimed that "the GOP budget will decimate local communities, blow an economic hole in rural America, and make us into a nation governed by and for a handful of elites."

House Republicans push back against the Democrats' attacks and say what they are doing is putting an end to waste, fraud and abuse currently in the Medicaid system, so the program can work for the public in the way that it was intended.

They call any talk that they are cutting aid to mothers, children, people with disabilities and the elderly a "flat out lie."

"Democrats are lying to protect a broken status quo that lets illegal immigrants siphon off billions meant for American families. We're strengthening Medicaid for future generations by protecting taxpayers and restoring integrity," Hudson added.

Dating back to last year's presidential campaign, Trump has vowed not to touch Medicaid. On Tuesday, as he made a rare stop on Capitol Hill to meet behind closed doors with House Republicans in order to shore up support for the bill, Trump's message to fiscally conservative lawmakers looking to make further cuts to Medicaid was "Don't f--- around with Medicaid."

While there are divisions between Republicans over Medicaid, and a chasm between the two major parties over the longstanding entitlement program, there is one point of agreement: This issue will continue to simmer on the campaign trail in one form or another long after the legislative battles on Capitol Hill are over.