- by cnn
- 15 Aug 2024
In February 2016, infectious disease epidemiologist Steffanie Strathdee was holding her dying husband's hand, watching him lose an exhausting fight against a deadly superbug infection.
After months of ups and downs, doctors had just told her that her husband, Tom Patterson, was too racked with bacteria to live.
"I told him, 'Honey, we're running out of time. I need to know if you want to live. I don't even know if you can hear me, but if you can hear me and you want to live, please squeeze my hand.'
"All of a sudden, he squeezed really hard. And I thought, 'Oh, great!' And then I'm thinking, 'Oh, crap! What am I going to do?'"
What she accomplished next could easily be called miraculous. First, Strathdee found an obscure treatment that offered a glimmer of hope - fighting superbugs with phages, viruses created by nature to eat bacteria.
Then she convinced phage scientists around the country to hunt and peck through molecular haystacks of sewage, bogs, ponds, the bilge of boats and other prime breeding grounds for bacteria and their viral opponents. The impossible goal: quickly find the few, exquisitely unique phages capable of fighting a specific strain of antibiotic-resistant bacteria literally eating her husband alive.
Next, the US Food and Drug Administration had to greenlight this unproven cocktail of hope, and scientists had to purify the mixture so that it wouldn't be deadly.
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